Characterization of Blood-Group-ABO(H)-Active Glycosphingolipids in Type-AB Human Erythrocytes
نویسندگان
چکیده
منابع مشابه
Characterization of neutral blood group B-active glycosphingolipids of rat gastric mucosa. A novel type of blood group active glycosphingolipid based on isogloboside.
The blood group active glycosphingolipids of rat gastric mucosa have been investigated. Only blood group B active structures were found, two of which have been structurally characterized by monoclonal antibodies, mass spectrometry, permethylation analyses, proton NMR spectroscopy, and exoglycosidase digestions. A six-sugar compound based on a gangliotetraosylceramide core was isolated and shown...
متن کاملNovel blood group H glycolipid antigens exclusively expressed in blood group A and AB erythrocytes (type 3 chain H). I. Isolation and chemical characterization.
A series of blood group H antigens reacting with monoclonal antibody MBrl has been found in human blood group A and AB erythrocytes, but not in O or B erythrocytes. These H antigens are clearly different from the globo-H structure (Fuc alpha 1----2Gal beta 1----3GalNAc beta 1----3Gal alpha 1----4Gal beta 1----4Glc beta 1----1Cer), which was previously isolated from O erythrocytes and is also re...
متن کاملComplex glycosphingolipids with blood-group A specificity.
The oligosaccharide chains present in blood-group ABH glycoproteins and glycolipids of glandular epithelial tissue exhibit a considerable degree of heterogeneity with respect to length of carbohydrate chains and degree of branching [l-6] . The sizes of the largest blood-group-active oligosaccharide chains from horse gastric mucosa are in the range of 812 sugar residues [7] , whereas those from ...
متن کاملChemical characterization and distribution of ABO blood group active glycoprotein in human erythrocyte membrane.
Occurrence and distribution of glycoprotein H substances in blood type O human erythrocyte membrance were studied using an alpha N-acetylgalactosaminyltransferase (A-enzyme) purified from milk of blood type A women. Erythrocytes of blood group O, nonsecretors and secretors alike, contain H substances that serve as a substrate for this transferase, and the H determinants seem to occur in all thr...
متن کاملCharacterization of neutral glycosphingolipids in human cataractous lens.
Neutral glycosphingolipids were purified from human senile cataractous lenses by a combination of solvent extraction, Folch's partition, acetylation, and column chromatography using DEAE-Sephadex and Iatrobeads. Six major glycosphingolipids (A-F) from monohexosylceramide to pentahexosylceramide were identified by sugar composition analysis, methylation analysis, secondary ion-mass spectrometry,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1995
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1995.0862d.x